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Post by Guest on Mon Aug 11, 2014 8:29 pm

Bee, snake and scorpion venom could be used to fight cancer Bee_2426517b
Neonicotinoid pesticides are new nicotine-like chemicals that act on the nervous systems of insects, and are blamed for damaging bees’ brains Photo: AP

Bee, snake and scorpion venom could be used in fight against cancer after trials showed that the toxins can kill tumours. Researchers have found the poison contained in insect stings or reptile bites kills breast and skin cancer cells in the lab.  And they have managed to encase the venom in a tiny particle which stops the poison leaking into the blood and harming the patient.

Dr Dipanjan Pan, of the University of Illinois, said: “We have safely used venom toxins in tiny nanometer-sized particles to treat breast cancer and melanoma cells in the laboratory. These particles, which are camouflaged from the immune system, take the toxin directly to the cancer cells, sparing normal tissue.  The peptide toxins we made are so tightly packed within the nanoparticle that they don't leach out when exposed to the bloodstream and cause side effects.”

Venom from snakes, bees and scorpions contains proteins and peptides which can attach to the walls of cancer cells.  But it can also damage the heart and nerve cells and cause bleeding under the skin

“The main point is how we can control their potency. They are potent and that is why they are deadly,” added Dr Pan.  “If we can use that power in our favour that would be wonderful.”

The team identified a substance in bee venom called melittin that keeps the cancer cells from multiplying.

Bees make so little venom that it us not feasible to extract it and separate out the substance time after time for lab testing or for later clinical use so they synthesized melittin in the lab.

The team believes that venom from snakes or scorpions, will also work well in the nanoparticles as a possible cancer therapy.  They are hoping to begin human trials within three to five years.  The research was presented at the National Meeting of the American Chemical Society in San Francisco.

http://www.telegraph.co.uk/science/science-news/11026321/Bee-snake-and-scorpion-venom-could-be-used-to-fight-cancer.html

This sounds like an amazing discovery, fingers and everything crossed  cheers

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Post by Ben Reilly on Mon Aug 11, 2014 8:46 pm

Amazing, especially the discovery that allows them to "sheath" the poison cells and target only cancerous tissue ...

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Post by Guest on Mon Aug 11, 2014 8:52 pm

Ben_Reilly wrote:Amazing, especially the discovery that allows them to "sheath" the poison cells and target only cancerous tissue ...

Combined with the leaps they are making in gene therapy, in a few years time chemo might be absolute. Come the day.

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Post by Guest on Mon Aug 11, 2014 8:54 pm

Ben_Reilly wrote:Amazing, especially the discovery that allows them to "sheath" the poison cells and target only cancerous tissue ...

I am really hopeful Ben, it sounds like a major step forward  I love you x

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Post by eddie on Mon Aug 11, 2014 9:57 pm

Sassy wrote:
Ben_Reilly wrote:Amazing, especially the discovery that allows them to "sheath" the poison cells and target only cancerous tissue ...

Combined with the leaps they are making in gene therapy, in a few years time chemo might be absolute.   Come the day.

I hope that chemo is chucked in the bin.
It's poison and it kills people.

I'd like to see cancer eradicated off the face of this earth, it has taken and disabled too many people x

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Post by Ben Reilly on Tue Aug 12, 2014 6:25 am

Lone Wolf wrote:cyclops 

AMAZING that this report turns up in a rag as unreliable as the Telegraph...

I'M always a bit dubious about seeing scientific and medical "breakthroughs" first in newspapers rather than 'peer reviewed' journals..    Suspect

MAKES me often wonder if they're still chasing research funding.

What do you make of this?

http://www.sciencedirect.com/science/article/pii/S0168365914001394

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Post by veya_victaous on Tue Aug 12, 2014 10:52 am

actually I have heard of the venom thing before.
There are people here studying the various snake venom to see if COMPONENTS may be useful...


And PS eds it would still technically be chemotherapy as it is 'Chemical Therapy' as opposed to radiotherapy that is 'Radiation therapy' .

Chemotherapy has gotten a bad name from the current drugs (but they are always improving) but it is actually a broader term and yet to be developed far superior treatments may still fall under it.

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Post by Raggamuffin on Tue Aug 12, 2014 11:05 am

The best way to target cancer is to target the immune cells which are aiding the tumours IMO.

Oh, and not all chemical treatment is chemotherapy.

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Post by HoratioTarr on Tue Aug 12, 2014 11:43 am

The drugs companies want us to be ill. It's huge business. Chemo keeps 'em all in fast cars and fucking high living.
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Post by veya_victaous on Tue Aug 12, 2014 12:23 pm

Raggamuffin wrote:The best way to target cancer is to target the immune cells which are aiding the tumours IMO.
Umm what? Immune cells don't aid cancer tumors  confused 
they don't detect them because they are 'biologically' part of the cancer patient, Immune cell only target cells that it deems to be NOT part of the person/lifeform/host, Cancer cells fall in the grey part in between, where they are our cells just mutated in away that is detrimental to our health. Part of the reason for the increase in cancer is that we live longer and our cell constantly regenerate and over time the 'blue print' for cells deteriorates (a.k.a aging) all it takes is one cell blueprint to deteriorate in a way that creates a cell that doesn't function but contains 'close enough' to the correct DNA that the Immune System says it is 'part of you' and you have a tumor. Cancer (generally there are different ones in bone/blood cancers, it is a broad an complex disease) is a cell that also has enough 'correct' genetic material to be able to replicate itself (something cells constantly do) the 'aggressiveness' of a cancer is at least partially related to the replication versus death rate of the cells. the Worst case scenarios the cells Don't die and replicate quickly and the fact bowel cancer is one of the most aggressive cancers is quite likely related to the fact bowel cells replicate rapidly by nature to cope with digestion

Oh, and not all chemical treatment is chemotherapy.
No but using Chemicals to destroy cells is, the third option is surgery to remove cells,
Treatment of cancer in some way, shape or form involves the removal of the affected cells



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Post by veya_victaous on Tue Aug 12, 2014 12:28 pm

I'll Add that no one that 'serious' about curing cancer is trying to cure all cancer with a single treatment.
The treatment and hopeful eventual cures will (pretty much 100% sure) be specific to the type of cancer.


Unless we replace our bodies with robots... Vote 1 Skynet  Cool 

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Post by Raggamuffin on Tue Aug 12, 2014 12:53 pm

veya_victaous wrote:
Raggamuffin wrote:The best way to target cancer is to target the immune cells which are aiding the tumours IMO.
Umm what? Immune cells don't aid cancer tumors  confused 
they don't detect them because they are 'biologically' part of the cancer patient, Immune cell only target cells that it deems to be NOT part of the person/lifeform/host, Cancer cells fall in the grey part in between, where they are our cells just mutated in away that is detrimental to our health. Part of the reason for the increase in cancer is that we live longer and our cell constantly regenerate and over time the 'blue print' for cells deteriorates (a.k.a aging) all it takes is one cell blueprint to deteriorate in a way that creates a cell that doesn't function but contains 'close enough' to the correct DNA that the Immune System says it is 'part of you' and you have a tumor. Cancer (generally there are different ones in bone/blood cancers, it is a broad an complex disease) is a cell that also has enough 'correct' genetic material to be able to replicate itself (something cells constantly do) the 'aggressiveness' of a cancer is at least partially related to the replication versus death rate of the cells. the Worst case scenarios the cells Don't die and replicate quickly and the fact bowel cancer is one of the most aggressive cancers is quite likely related to the fact bowel cells replicate rapidly by nature to cope with digestion

Oh, and not all chemical treatment is chemotherapy.
No but using Chemicals to destroy cells is, the third option is surgery to remove cells,
Treatment of cancer in some way, shape or form involves the removal of the affected cells



Immune cells do aid cancer. The immune systems searches out and destroys rogue cells, but for some reason parts of it it can be hijacked and used to help tumours grow.

Treatment can also include preventing the tumour cells from replicating, which is not the same thing as removing or killing them.

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